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Ellen Pompeo reacts to Justin Chambers leaving Grey’s Anatomy

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It’s been a sad few days forGrey’s Anatomyfans.
On Friday,Justin Chambersshocked everyone by announcing that not only hashe left the ABC medical drama after 15 years, but his final appearance has also already aired. And early Saturday, his longtime costarEllen Pompeo, now the only remaining originalGrey’s Anatomyintern from the beginning of the series, reacted to the of his departure.

WhenVanity Fairtweeted that “Grey’s Anatomyis about to feel one of its biggest losses yet,” Pompeoquote-tweetedit with the comment, “Truer words have never been spoken,” along with the broken heart emoji.

“There’s no good time to say goodbye to a show and character that’s defined so much of my for the past 15 years,” Chambers previously said in a statement toDeadline when he announced his departure from Shonda Rhimes’ iconic series. “For some time now, however, I have hoped to diversify my acting roles and career choices. And, as I turn 50 and am blessed with my remarkable, supportive wife and five wonderful children, now is that time. As I move on fromGrey’s Anatomy, I want to thank the ABC family, Shonda Rimes, original cast members Ellen Pompeo, Chandra Wilson and James Pickens, and the rest of the amazing cast and crew, both past and present, and, of course, the fans for an extraordinary ride.”

Chambers’ final episode airedon November 14, and the November 21 episode mentioned thatAlex had returned hometo take care of his mom. There’s no word yet on how Chambers’ absence from the series will be explained on the show.
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